There’s saying no to reporters, then there’ saying no to the president:
Still being talked about for secretary of state, Indiana Senator Dick Lugar continues to say “no thanks” and would tell Barack Obama that if he calls.
[. . .]
“I feel that I can do the most for my state for my country by serving in the United States Senate,” said Indiana’s senior senator.
If he’s asked and says no, he says no. But I can think of a lot worse people to have in the secretary of state’s office, and most of them are probably on Obama’s list.